Penfield ReferenceA quantitative reference for the human brain.
Penfield Reference compares individual brains and research cohorts against large collections of healthy normative imaging data.
Instead of asking whether a measurement looks unusual, Reference asks how far it sits from what would be expected for a matched healthy population, in standard deviations, percentiles and longitudinal change.
Discuss a research collaborationHow Penfield Reference works
Every measurement,
in population context.
An individual or cohort is segmented, measured and compared against a matched healthy reference distribution. The same regions, the same units: a consistent way to read difference.
PF–001Analysis complete
Designed for investigation. Not for clinical diagnosis.
Illustrative interface · Synthetic dataMatched before
it is compared.
Deviation only means something against the right reference. Reference aims to match each scan against a healthy population selected for the variables that shape anatomy.
- 01Age
- 02Sex
- 03Scanner
- 04Field strength
- 05Acquisition protocol
- 06Intracranial volume
- 07Reference cohort
Planned capabilities
- 01Regional structure volumes
- 02Cortical thickness
- 03Hemispheric asymmetry
- 04Population percentiles
- 05Deviation scores
- 06Cohort analysis
- 07Longitudinal analysis
- 08Integration with Fusion and Findings
Findings from Penfield Findings can be read against the same reference distributions, so what is detected and how unusual it is stay connected. Open in Fusion Analyse with Findings
One system
Every Penfield product sits on the same path: measurement in, intervention out. Penfield Reference is one part of it.
Observe & Understand
Understand
Simulate